The Role of Myelogram in Diagnosis of Malignant Hemopathies

Skali Hajar; Lazrak Fatima Zahrae; Yahyaoui Hicham; Ait Ameur Mustapha; Chakour Mohamed

doi:doi:10.11648/j.ajlm.20210605.11

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The Role of Myelogram in Diagnosis of Malignant Hemopathies

Skali Hajar, Lazrak Fatima Zahrae, Yahyaoui Hicham, Ait Ameur Mustapha, Chakour Mohamed

Published in American Journal of Laboratory Medicine (Volume 6, Issue 5)

Received: 18 September 2021 Accepted: 5 October 2021 Published: 12 October 2021

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Abstract

The myelogram is an essential investigation for the diagnosis and management of malignant hemopathies. The final interpretation requires the integration of peripheral blood count and smear, with the results of supplementary tests such as immunophenotyping, cytogenetic analysis and molecular genetic studies as appropriate, in the context of clinical and other diagnostic findings. This retrospective study conducted at the Hematology Laboratory of the Military hospital Avicenna in Marrakech over a period of two years, from January 2018 to December 2019, aimed to evaluate the practice and the contribution of the myelogram in diagnosis in patients in the Hematology Laboratory and to report the epidemiological profile of malignant hemopathies diagnosed in our Laboratory. In our study, out of 420 myelograms received in the Hematology Laboratory of the military hospital in Marrakech, 70 cases (17%) of malignant hemopathies were collected. The predominant age range was 61 to 70 years old. The male gender was predominant (64%) with a sex-ratio at 1,8. The clinical indications of myelogram were dominated by anemic syndrome, tumoral syndrome. Biologically, the Peripheral Blood count and smear abnormalities were the most frequent. Acute leukemias were accounted for 35% of all malignant pathologies diagnosed in our laboratory of which 79% myeloid, 21% lymphoid. Multiple myelomas were found in 33%, myelodysplastic syndromes in 17% and Chronic myeloid leukemia in 9%. The role of the myelogram in diagnostic of malignant hemopathies is based on its good interpretation which is directly linked to the rigor of its realization.

Published in	American Journal of Laboratory Medicine (Volume 6, Issue 5)
DOI	10.11648/j.ajlm.20210605.11
Page(s)	70-76
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Myelogram, Bone Marrow Smear, Blood Smear, Malignant Hemopathy, Leukemia

References

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[12]	Ouattara S, Danho B, Kone M, Tea D. (2000) La pratique du myélogramme au chu de Treichville: bilan de 19 années d’activité. [The practice of the myelogram at the University hospital of Treichville: review of 19 years of activity] Médecine d'Afrique Noire; 47, 5.
[13]	El Hamdaoui O. (2018) Apport du myélogramme dans le diagnostic des hémopathies: expérience du laboratoire central d’hématologie de l’Hôpital IBN SINA RABAT. [Contribution of the myelogram in the diagnosis of hemopathies: experience of the central hematology laboratory of the IBN SINA RABAT Hospital]. Thèse de médecine, Rabat; N 22.
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APA Style

Skali Hajar, Lazrak Fatima Zahrae, Yahyaoui Hicham, Ait Ameur Mustapha, Chakour Mohamed. (2021). The Role of Myelogram in Diagnosis of Malignant Hemopathies. American Journal of Laboratory Medicine, 6(5), 70-76. https://doi.org/10.11648/j.ajlm.20210605.11

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ACS Style

Skali Hajar; Lazrak Fatima Zahrae; Yahyaoui Hicham; Ait Ameur Mustapha; Chakour Mohamed. The Role of Myelogram in Diagnosis of Malignant Hemopathies. Am. J. Lab. Med. 2021, 6(5), 70-76. doi: 10.11648/j.ajlm.20210605.11

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AMA Style

Skali Hajar, Lazrak Fatima Zahrae, Yahyaoui Hicham, Ait Ameur Mustapha, Chakour Mohamed. The Role of Myelogram in Diagnosis of Malignant Hemopathies. Am J Lab Med. 2021;6(5):70-76. doi: 10.11648/j.ajlm.20210605.11

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@article{10.11648/j.ajlm.20210605.11,
  author = {Skali Hajar and Lazrak Fatima Zahrae and Yahyaoui Hicham and Ait Ameur Mustapha and Chakour Mohamed},
  title = {The Role of Myelogram in Diagnosis of Malignant Hemopathies},
  journal = {American Journal of Laboratory Medicine},
  volume = {6},
  number = {5},
  pages = {70-76},
  doi = {10.11648/j.ajlm.20210605.11},
  url = {https://doi.org/10.11648/j.ajlm.20210605.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajlm.20210605.11},
  abstract = {The myelogram is an essential investigation for the diagnosis and management of malignant hemopathies. The final interpretation requires the integration of peripheral blood count and smear, with the results of supplementary tests such as immunophenotyping, cytogenetic analysis and molecular genetic studies as appropriate, in the context of clinical and other diagnostic findings. This retrospective study conducted at the Hematology Laboratory of the Military hospital Avicenna in Marrakech over a period of two years, from January 2018 to December 2019, aimed to evaluate the practice and the contribution of the myelogram in diagnosis in patients in the Hematology Laboratory and to report the epidemiological profile of malignant hemopathies diagnosed in our Laboratory. In our study, out of 420 myelograms received in the Hematology Laboratory of the military hospital in Marrakech, 70 cases (17%) of malignant hemopathies were collected. The predominant age range was 61 to 70 years old. The male gender was predominant (64%) with a sex-ratio at 1,8. The clinical indications of myelogram were dominated by anemic syndrome, tumoral syndrome. Biologically, the Peripheral Blood count and smear abnormalities were the most frequent. Acute leukemias were accounted for 35% of all malignant pathologies diagnosed in our laboratory of which 79% myeloid, 21% lymphoid. Multiple myelomas were found in 33%, myelodysplastic syndromes in 17% and Chronic myeloid leukemia in 9%. The role of the myelogram in diagnostic of malignant hemopathies is based on its good interpretation which is directly linked to the rigor of its realization.},
 year = {2021}
}

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TY  - JOUR
T1  - The Role of Myelogram in Diagnosis of Malignant Hemopathies
AU  - Skali Hajar
AU  - Lazrak Fatima Zahrae
AU  - Yahyaoui Hicham
AU  - Ait Ameur Mustapha
AU  - Chakour Mohamed
Y1  - 2021/10/12
PY  - 2021
N1  - https://doi.org/10.11648/j.ajlm.20210605.11
DO  - 10.11648/j.ajlm.20210605.11
T2  - American Journal of Laboratory Medicine
JF  - American Journal of Laboratory Medicine
JO  - American Journal of Laboratory Medicine
SP  - 70
EP  - 76
PB  - Science Publishing Group
SN  - 2575-386X
UR  - https://doi.org/10.11648/j.ajlm.20210605.11
AB  - The myelogram is an essential investigation for the diagnosis and management of malignant hemopathies. The final interpretation requires the integration of peripheral blood count and smear, with the results of supplementary tests such as immunophenotyping, cytogenetic analysis and molecular genetic studies as appropriate, in the context of clinical and other diagnostic findings. This retrospective study conducted at the Hematology Laboratory of the Military hospital Avicenna in Marrakech over a period of two years, from January 2018 to December 2019, aimed to evaluate the practice and the contribution of the myelogram in diagnosis in patients in the Hematology Laboratory and to report the epidemiological profile of malignant hemopathies diagnosed in our Laboratory. In our study, out of 420 myelograms received in the Hematology Laboratory of the military hospital in Marrakech, 70 cases (17%) of malignant hemopathies were collected. The predominant age range was 61 to 70 years old. The male gender was predominant (64%) with a sex-ratio at 1,8. The clinical indications of myelogram were dominated by anemic syndrome, tumoral syndrome. Biologically, the Peripheral Blood count and smear abnormalities were the most frequent. Acute leukemias were accounted for 35% of all malignant pathologies diagnosed in our laboratory of which 79% myeloid, 21% lymphoid. Multiple myelomas were found in 33%, myelodysplastic syndromes in 17% and Chronic myeloid leukemia in 9%. The role of the myelogram in diagnostic of malignant hemopathies is based on its good interpretation which is directly linked to the rigor of its realization.
VL  - 6
IS  - 5
ER  -

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Author Information

Skali Hajar

Hematology Laboratory Military Hospital Avicenna of Marrakech, Faculty of Medicine and Pharmacy of Marrakech, University of Cadi Ayyad of Marrakech, Marrakech, Morocco
Lazrak Fatima Zahrae

Hematology Laboratory Military Hospital Avicenna of Marrakech, Faculty of Medicine and Pharmacy of Marrakech, University of Cadi Ayyad of Marrakech, Marrakech, Morocco
Yahyaoui Hicham

Hematology Laboratory Military Hospital Avicenna of Marrakech, Faculty of Medicine and Pharmacy of Marrakech, University of Cadi Ayyad of Marrakech, Marrakech, Morocco
Ait Ameur Mustapha

Hematology Laboratory Military Hospital Avicenna of Marrakech, Faculty of Medicine and Pharmacy of Marrakech, University of Cadi Ayyad of Marrakech, Marrakech, Morocco
Chakour Mohamed

Hematology Laboratory Military Hospital Avicenna of Marrakech, Faculty of Medicine and Pharmacy of Marrakech, University of Cadi Ayyad of Marrakech, Marrakech, Morocco

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APA Style

Skali Hajar, Lazrak Fatima Zahrae, Yahyaoui Hicham, Ait Ameur Mustapha, Chakour Mohamed. (2021). The Role of Myelogram in Diagnosis of Malignant Hemopathies. American Journal of Laboratory Medicine, 6(5), 70-76. https://doi.org/10.11648/j.ajlm.20210605.11

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ACS Style

Skali Hajar; Lazrak Fatima Zahrae; Yahyaoui Hicham; Ait Ameur Mustapha; Chakour Mohamed. The Role of Myelogram in Diagnosis of Malignant Hemopathies. Am. J. Lab. Med. 2021, 6(5), 70-76. doi: 10.11648/j.ajlm.20210605.11

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AMA Style

Skali Hajar, Lazrak Fatima Zahrae, Yahyaoui Hicham, Ait Ameur Mustapha, Chakour Mohamed. The Role of Myelogram in Diagnosis of Malignant Hemopathies. Am J Lab Med. 2021;6(5):70-76. doi: 10.11648/j.ajlm.20210605.11

Copy | Download

@article{10.11648/j.ajlm.20210605.11,
  author = {Skali Hajar and Lazrak Fatima Zahrae and Yahyaoui Hicham and Ait Ameur Mustapha and Chakour Mohamed},
  title = {The Role of Myelogram in Diagnosis of Malignant Hemopathies},
  journal = {American Journal of Laboratory Medicine},
  volume = {6},
  number = {5},
  pages = {70-76},
  doi = {10.11648/j.ajlm.20210605.11},
  url = {https://doi.org/10.11648/j.ajlm.20210605.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajlm.20210605.11},
  abstract = {The myelogram is an essential investigation for the diagnosis and management of malignant hemopathies. The final interpretation requires the integration of peripheral blood count and smear, with the results of supplementary tests such as immunophenotyping, cytogenetic analysis and molecular genetic studies as appropriate, in the context of clinical and other diagnostic findings. This retrospective study conducted at the Hematology Laboratory of the Military hospital Avicenna in Marrakech over a period of two years, from January 2018 to December 2019, aimed to evaluate the practice and the contribution of the myelogram in diagnosis in patients in the Hematology Laboratory and to report the epidemiological profile of malignant hemopathies diagnosed in our Laboratory. In our study, out of 420 myelograms received in the Hematology Laboratory of the military hospital in Marrakech, 70 cases (17%) of malignant hemopathies were collected. The predominant age range was 61 to 70 years old. The male gender was predominant (64%) with a sex-ratio at 1,8. The clinical indications of myelogram were dominated by anemic syndrome, tumoral syndrome. Biologically, the Peripheral Blood count and smear abnormalities were the most frequent. Acute leukemias were accounted for 35% of all malignant pathologies diagnosed in our laboratory of which 79% myeloid, 21% lymphoid. Multiple myelomas were found in 33%, myelodysplastic syndromes in 17% and Chronic myeloid leukemia in 9%. The role of the myelogram in diagnostic of malignant hemopathies is based on its good interpretation which is directly linked to the rigor of its realization.},
 year = {2021}
}

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TY  - JOUR
T1  - The Role of Myelogram in Diagnosis of Malignant Hemopathies
AU  - Skali Hajar
AU  - Lazrak Fatima Zahrae
AU  - Yahyaoui Hicham
AU  - Ait Ameur Mustapha
AU  - Chakour Mohamed
Y1  - 2021/10/12
PY  - 2021
N1  - https://doi.org/10.11648/j.ajlm.20210605.11
DO  - 10.11648/j.ajlm.20210605.11
T2  - American Journal of Laboratory Medicine
JF  - American Journal of Laboratory Medicine
JO  - American Journal of Laboratory Medicine
SP  - 70
EP  - 76
PB  - Science Publishing Group
SN  - 2575-386X
UR  - https://doi.org/10.11648/j.ajlm.20210605.11
AB  - The myelogram is an essential investigation for the diagnosis and management of malignant hemopathies. The final interpretation requires the integration of peripheral blood count and smear, with the results of supplementary tests such as immunophenotyping, cytogenetic analysis and molecular genetic studies as appropriate, in the context of clinical and other diagnostic findings. This retrospective study conducted at the Hematology Laboratory of the Military hospital Avicenna in Marrakech over a period of two years, from January 2018 to December 2019, aimed to evaluate the practice and the contribution of the myelogram in diagnosis in patients in the Hematology Laboratory and to report the epidemiological profile of malignant hemopathies diagnosed in our Laboratory. In our study, out of 420 myelograms received in the Hematology Laboratory of the military hospital in Marrakech, 70 cases (17%) of malignant hemopathies were collected. The predominant age range was 61 to 70 years old. The male gender was predominant (64%) with a sex-ratio at 1,8. The clinical indications of myelogram were dominated by anemic syndrome, tumoral syndrome. Biologically, the Peripheral Blood count and smear abnormalities were the most frequent. Acute leukemias were accounted for 35% of all malignant pathologies diagnosed in our laboratory of which 79% myeloid, 21% lymphoid. Multiple myelomas were found in 33%, myelodysplastic syndromes in 17% and Chronic myeloid leukemia in 9%. The role of the myelogram in diagnostic of malignant hemopathies is based on its good interpretation which is directly linked to the rigor of its realization.
VL  - 6
IS  - 5
ER  -

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